iPTMnet Report Q9NR81 ARHGEF3

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NR81 / ARHG3_HUMAN
Protein Name	Rho guanine nucleotide exchange factor 3
Gene Name	Name: ARHGEF3
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NR81 DAG View
PRO Name	Rho guanine nucleotide exchange factor 3 (human)
Definition	A Rho guanine nucleotide exchange factor 3 that is encoded in the genome of human.
Short Label	hARHGEF3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NR81 (ARHGEF3) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S43	Phosphorylation		score1	PhosphoSitePlus
	S47	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
	K56	Ubiquitination		score1	PhosphoSitePlus
	S64	Phosphorylation		score1	PhosphoSitePlus
	K146	Ubiquitination		score1	PhosphoSitePlus
	K249	Ubiquitination		score1	PhosphoSitePlus
	K265	Ubiquitination		score1	PhosphoSitePlus
	K325	Ubiquitination		score1	PhosphoSitePlus
	K342	Ubiquitination		score1	PhosphoSitePlus
	K382	Ubiquitination		score1	PhosphoSitePlus
	S399	Phosphorylation		score1	PhosphoSitePlus
	K411	Ubiquitination		score1	PhosphoSitePlus
	K419	Ubiquitination		score1	PhosphoSitePlus
	K437	Ubiquitination		score1	PhosphoSitePlus
	S466	Phosphorylation		score1	PhosphoSitePlus
	S524	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S35	Phosphorylation		score1	PhosphoSitePlus
	S79	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S47	L47	Biomuta		DOID:1909 / melanoma [ icgc, tcga ]