iPTMnet Report for Q9NR34 (MAN1C1)
Protein Information
| UniProt AC / UniProt ID | Q9NR34 / MA1C1_HUMAN |
| Protein Name | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC |
| Gene Name | Name: MAN1C1 Synonyms:MAN1A3,MAN1C; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NR34 |
| PRO Name | mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (human) |
| Definition | A mannosyl-oligosaccharide 1,2-alpha-mannosidase IC that is encoded in the genome of human. |
| Short Label | hMAN1C1 |
| Category | organism-gene |
Q9NR34 (MAN1C1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T58 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S98 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S128 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| S132 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
| S132 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 16964243 | ||
| T159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S164 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20166139, 24275569 | ||
| S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K447 | Acetylation | score1 | PhosphoSitePlus | |||
| K554 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T58 | A58 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T159 | M159 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] |
DAG View