iPTMnet Report for Q9NR12 (PDLIM7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NR12 / PDLI7_HUMAN
Protein Name PDZ and LIM domain protein 7
Gene Name Name: PDLIM7
Synonyms:ENIGMA;
Organism Homo sapiens (Human)

PRO ID PR:Q9NR12
DAG View
PRO Name PDZ and LIM domain protein 7 (human)
Definition A PDZ and LIM domain protein 7 that is encoded in the genome of human.
Short Label hPDLIM7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NR12 (PDLIM7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus   RLIMS-P 22266808
S60 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus   UniProt 23186163
S82 Phosphorylation PhosphoSitePlus
S89 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 35254053, 32119511, 35289036, 29351928, 21158410, 20068230
S95 O-Glycosylation GlyGen 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 35254053, 32119511, 35289036, 29351928, 21158410, 20068230
S95 Phosphorylation PhosphoSitePlus
A96 Phosphorylation PhosphoSitePlus
R103 Methylation PhosphoSitePlus   UniProt 24129315
Y104 Phosphorylation PhosphoSitePlus
T105 O-Glycosylation GlyGen 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 35254053, 32119511, 35289036, 29351928, 21158410, 29237092, 20068230
T105 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus   UniProt 23186163
K114 Ubiquitination PhosphoSitePlus
R117 Methylation PhosphoSitePlus
R137 Methylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K145 Methylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
R165 Methylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
T196 O-Glycosylation GlyGen 34846842, 33214551, 32938750, ...35138101, 32870666, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 35254053, 32119511, 35289036, 29351928, 21158410, 20068230
S203 O-Glycosylation GlyGen 34846842
S204 O-Glycosylation GlyGen 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 35254053, 32119511, 35289036, 29351928, 21158410, 20068230
T205 Phosphorylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
S217 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y234 Phosphorylation PhosphoSitePlus
K238 Sumoylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
T239 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 23584533, 35254053, 32119511, 35289036, 29351928, 21158410, 20068230
S240 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 23584533, 35254053, 32119511, 35289036, 29351928, 21158410, 29237092, 20068230
T241 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T241 Phosphorylation PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
S247 O-Glycosylation GlyGen 33214551, 35138101, 32870666, ...30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 35254053, 32119511, 35289036, 29351928, 21158410, 20068230
S247 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T251 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
T253 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S78 Phosphorylation HPRD 20068231
S111 Phosphorylation HPRD 20068231
S217 Phosphorylation HPRD 18669648, 18452278
S247 Phosphorylation HPRD 18669648, 20068231
T251 Phosphorylation HPRD 18669648, 20068231, 17924679
Site PTM Type PTM Enzyme Score Source PMID
S78 Phosphorylation HPRD 20068231
T96 Phosphorylation PhosphoSitePlus
S183 Phosphorylation HPRD 18669648, 18452278
S213 Phosphorylation HPRD 18669648, 20068231
T217 Phosphorylation HPRD 18669648, 20068231, 17924679
Site PTM Type PTM Enzyme Score Source PMID
S78 Phosphorylation HPRD 20068231
Y104 Phosphorylation PhosphoSitePlus
S111 Phosphorylation HPRD 20068231
T161 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S89 I89 Biomuta DOID:184 / bone cancer [ cosmic ]
S95 P95 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc, cosmic ]
Y104 N104 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T214 N214 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T259 I259 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S260 F260 Biomuta DOID:4159 / skin cancer [ cosmic ]
K450 N450 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]