iPTMnet Report for Q9NQW5 (PRDM7)
Protein Information
UniProt AC / UniProt ID | Q9NQW5 / PRDM7_HUMAN |
Protein Name | Histone-lysine N-methyltransferase PRDM7 |
Gene Name | Name: PRDM7 Synonyms:PFM4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NQW5 |
PRO Name | histone-lysine N-methyltransferase PRDM7 (human) |
Definition | A histone-lysine N-methyltransferase PRDM7 that is encoded in the genome of human. |
Short Label | hPRDM7 |
Category | organism-gene |
Q9NQW5 (PRDM7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
K25 | Ubiquitination | score1 | PhosphoSitePlus | |||
K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
T69 | Phosphorylation | score1 | PhosphoSitePlus | |||
K102 | Sumoylation | score1 | PhosphoSitePlus | |||
T176 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y181 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y191 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
S143 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T69 | A69 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |