Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQT5 / EXOS3_HUMAN
Protein Name Exosome complex component RRP40
Gene Name Name: EXOSC3
Synonyms:RRP40;ORFNames:CGI-102;
Organism Homo sapiens (Human)

PRO ID PR:Q9NQT5
DAG View
PRO Name exosome complex component RRP40 (human)
Definition An exosome complex component RRP40 that is encoded in the genome of human.
Short Label hEXOSC3
Category organism-gene

Interactive Sequence View

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Q9NQT5 (EXOSC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
K82 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S161 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K89 * Biomuta DOID:1612 / breast cancer [ icgc ]
K124 N124 Biomuta DOID:1612 / breast cancer [ cosmic ]