iPTMnet Report for Q9NQS1 (AVEN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQS1 / AVEN_HUMAN
Protein Name Cell death regulator Aven
Gene Name Name: AVEN
Organism Homo sapiens (Human)

PRO ID PR:Q9NQS1
DAG View
PRO Name cell death regulator Aven (human)
Definition A cell death regulator Aven that is encoded in the genome of human.
Short Label hAVEN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NQS1 (AVEN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R17 Methylation PhosphoSitePlus
R28 Methylation PhosphoSitePlus
R37 Methylation PhosphoSitePlus
R50 Methylation PhosphoSitePlus
S94 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 19651622, ...18669648, 15345747
T98 Phosphorylation HPRD 17081983
Y99 Phosphorylation HPRD 17081983
Y109 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
S135 Phosphorylation Q13315 (ATM) neXtProt   PhosphoSitePlus 18571408
S151 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K230 Methylation PhosphoSitePlus   UniProt 24129315
K230 Ubiquitination PhosphoSitePlus
R238 Methylation PhosphoSitePlus
K245 Methylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
S261 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S265 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
S273 Phosphorylation HPRD   PhosphoSitePlus 20068231
S308 Phosphorylation Q13315 (ATM) HPRD   neXtProt   PhosphoSitePlus 18571408, 20068231
C326 S-Nitrosylation dbSNO 26338901
S330 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S116 T116 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S116 F116 Biomuta DOID:4159 / skin cancer [ cosmic ]
S135 L135 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K215 R215 Biomuta DOID:363 / uterine cancer [ icgc ]
K245 N245 Biomuta DOID:1324 / lung cancer [ cosmic ]
S268 C268 Biomuta DOID:1324 / lung cancer [ cosmic ]
S268 Y268 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S273 F273 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C326 F326 Biomuta DOID:1324 / lung cancer [ cosmic ]