iPTMnet Report for Q9NQG7 (HPS4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQG7 / HPS4_HUMAN
Protein Name BLOC-3 complex member HPS4
Gene Name Name: HPS4
Synonyms:KIAA1667;
Organism Homo sapiens (Human)

PRO ID PR:Q9NQG7
DAG View
PRO Name BLOC-3 complex member HPS4 (human)
Definition A BLOC-3 complex member HPS4 that is encoded in the genome of human.
Short Label hHPS4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NQG7 (HPS4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K167 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S355 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 23186163, 19690332
T530 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
Y544 Phosphorylation PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
T650 Phosphorylation IEDB 32387766
K702 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S355 Phosphorylation HPRD 18088087, 19664994
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S350 Phosphorylation HPRD 18088087, 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K167 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K212 N212 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
S289 I289 Biomuta DOID:9256 / colorectal cancer [ cosmic ]