iPTMnet Report for Q9NQB0 (TCF7L2)
Protein Information
| UniProt AC / UniProt ID | Q9NQB0 / TF7L2_HUMAN |
| Protein Name | Transcription factor 7-like 2 |
| Gene Name | Name: TCF7L2 Synonyms:TCF4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NQB0 |
| PRO Name | transcription factor 7-like 2 (human) |
| Definition | A transcription factor 7-like 2 that is encoded in the genome of human. |
| Short Label | hTCF7L2 |
| Category | organism-gene |
Q9NQB0 (TCF7L2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K22 | Sumoylation | score1 | PhosphoSitePlus | |||
| S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S58 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
| S59 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
| S60 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R126 | Methylation | score1 | PhosphoSitePlus | |||
| Y151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K173 | Acetylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | Q9UKE5 (TNIK) | score3 | neXtProt PhosphoSitePlus Signor | 20530691 | |
| S179 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T201 | Phosphorylation | Q9UBE8 (NLK) | score3 | neXtProt PRO PhosphoSitePlus Signor UniProt | 12556497 | |
| T212 | Phosphorylation | Q9UBE8 (NLK) | score3 | neXtProt PRO PhosphoSitePlus Signor UniProt | 12556497 | |
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K335 | Acetylation | score1 | PhosphoSitePlus | |||
| K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K362 | Acetylation | score1 | PhosphoSitePlus | |||
| K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K367 | Acetylation | score1 | PhosphoSitePlus | |||
| C372 | Methylation | score1 | IEDB | 33981976, 31844290 | ||
| K398 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y400 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y414 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y489 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K563 | Acetylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K433 | Sumoylation | score1 | PhosphoSitePlus | |||
| K442 | Sumoylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000049408 (hTCF7L2/Phos:1) | pT201,pT212 | PRO |
Proteoform PPIs
| Protein 1 | Relation | Protein 2 | Source | PMID | |
|---|---|---|---|---|---|
| PR:000037190 (hCTNNB1/iso:1/Phos:7) | decreased Interaction | PR:Q9NQB0 (hTCF7L2) | PRO | 23617586 |
DAG View