Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NQA5 / TRPV5_HUMAN
Protein Name Transient receptor potential cation channel subfamily V member 5
Gene Name Name: TRPV5
Organism Homo sapiens (Human)

DAG View
PRO Name transient receptor potential cation channel subfamily V member 5 (human)
Definition A transient receptor potential cation channel subfamily V member 5 that is encoded in the genome of human.
Short Label hTRPV5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NQA5 (TRPV5) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K42 Acetylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus   RLIMS-P 23024298
T148 Phosphorylation PhosphoSitePlus
S299 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 17006539
N358 N-Glycosylation GlyGen   UniProt 18768590
Y647 Phosphorylation PhosphoSitePlus
S654 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 17006539
S669 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
T685 Phosphorylation phospho.ELM 18669648
S689 Phosphorylation phospho.ELM 18669648
T708 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 24828496

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S142 N142 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ tcga ]
T148 R148 Biomuta DOID:1324 / lung cancer [ tcga ]
S654 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
S669 C669 Biomuta DOID:1612 / breast cancer [ cosmic ]
S689 Y689 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]