iPTMnet Report for Q9NPI1 (BRD7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPI1 / BRD7_HUMAN
Protein Name Bromodomain-containing protein 7
Gene Name Name: BRD7
Synonyms:BP75,CELTIX1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NPI1
DAG View
PRO Name bromodomain-containing protein 7 (human)
Definition A bromodomain-containing protein 7 that is encoded in the genome of human.
Short Label hBRD7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPI1 (BRD7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Acetylation PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
K21 Sumoylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K127 Sumoylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus   RLIMS-P 33101843
T260 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus   RLIMS-P 33101843
S265 Phosphorylation PhosphoSitePlus
S279 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S289 Phosphorylation PhosphoSitePlus   UniProt 23186163
S291 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
K328 Acetylation PhosphoSitePlus
S336 Phosphorylation RLIMS-P 33101843
S380 Phosphorylation PhosphoSitePlus   UniProt 23186163
K389 Ubiquitination PhosphoSitePlus
T502 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
T514 Phosphorylation PhosphoSitePlus   UniProt 23186163
R517 Methylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus   UniProt 24275569
S651 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S279 Phosphorylation HPRD 17081983, 20068231
S621 Phosphorylation HPRD 18452278


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P67809 (YBX1) S102 Q9NPI1 (BRD7) unknown eFIP 32028981


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K7 E7 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S41 I41 Biomuta DOID:1324 / lung cancer [ cosmic ]
S157 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K197 N197 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S265 T265 Biomuta DOID:1324 / lung cancer [ cosmic ]
T502 A502 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S512 P512 Biomuta DOID:263 / kidney cancer [ cosmic ]