Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPH3 / IL1AP_HUMAN
Protein Name Interleukin-1 receptor accessory protein precursor
Gene Name Name: IL1RAP
Synonyms:C3orf13,IL1R3;
Organism Homo sapiens (Human)

PRO ID PR:Q9NPH3
DAG View
PRO Name interleukin-1 receptor accessory protein (human)
Definition An interleukin-1 receptor accessory protein that is encoded in the genome of human.
Short Label hIL1RAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPH3 (IL1RAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T104 Phosphorylation PhosphoSitePlus
N107 N-Glycosylation UniProt 20802483
N111 N-Glycosylation UniProt 20802483
Y112 Phosphorylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
N118 N-Glycosylation UniProt 20802483
K134 Acetylation PhosphoSitePlus
K143 Acetylation PhosphoSitePlus
N209 N-Glycosylation UniProt 20802483
T293 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
S556 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S557 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S563 Phosphorylation PhosphoSitePlus
Y564 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S556 Phosphorylation HPRD 18669648, 20068231
S557 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K134 N134 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S305 I305 Biomuta DOID:3070 / malignant glioma [ tcga ]
K518 N518 Biomuta DOID:363 / uterine cancer [ tcga ]
S556 I556 Biomuta DOID:3571 / liver cancer [ icgc ]