iPTMnet Report for Q9NPH2 (ISYNA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPH2 / INO1_HUMAN
Protein Name Inositol-3-phosphate synthase 1
Gene Name Name: ISYNA1
Synonyms:INO1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NPH2
DAG View
PRO Name inositol-3-phosphate synthase 1 (human)
Definition An inositol-3-phosphate synthase 1 that is encoded in the genome of human.
Short Label hISYNA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPH2 (ISYNA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
R208 Methylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S279 Phosphorylation UniProt 23902760
K305 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
S357 Phosphorylation UniProt 23902760
S392 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
C437 Methylation IEDB 31844290
S473 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
K516 Methylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus
Y525 Phosphorylation PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
T538 Phosphorylation PhosphoSitePlus
T557 Phosphorylation PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R208 C208 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S357 R357 Biomuta DOID:3571 / liver cancer [ cosmic ]
S473 R473 Biomuta DOID:2531 / hematologic cancer [ cosmic ]