iPTMnet Report for Q9NPG3 (UBN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPG3 / UBN1_HUMAN
Protein Name Ubinuclein-1
Gene Name Name: UBN1
Organism Homo sapiens (Human)

PRO ID PR:Q9NPG3
DAG View
PRO Name ubinuclein-1 (human)
Definition A ubinuclein-1 that is encoded in the genome of human.
Short Label hUBN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPG3 (UBN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus   UniProt 23186163
S173 Phosphorylation PhosphoSitePlus   UniProt 17081983
S175 Phosphorylation PhosphoSitePlus   UniProt 17081983
S187 Phosphorylation PhosphoSitePlus
K222 Acetylation PhosphoSitePlus   UniProt 19608861
S231 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus   UniProt 24275569
S327 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus   UniProt 19690332, 20068231
S338 Phosphorylation PhosphoSitePlus   UniProt 20068231
S351 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
C420 Methylation IEDB 31844290
K474 Ubiquitination PhosphoSitePlus
K477 Acetylation PhosphoSitePlus
S493 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 17081983, ...24275569
K530 Sumoylation PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
K573 Methylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus   UniProt 20068231, 19690332, 24275569
S671 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus   UniProt 19690332
S764 Phosphorylation PhosphoSitePlus
S790 O-Glycosylation GlyGen 34846842
T818 Phosphorylation PhosphoSitePlus
S821 Phosphorylation PhosphoSitePlus
K826 Acetylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
S857 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
T861 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S862 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S866 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S868 O-Glycosylation GlyGen 34846842
S869 O-Glycosylation GlyGen 34846842
S870 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S872 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
T875 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S878 O-Glycosylation GlyGen   IEDB 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S879 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S880 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S881 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S884 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
K888 Acetylation PhosphoSitePlus
S891 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S894 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S897 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S898 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S977 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
T981 Phosphorylation PhosphoSitePlus
T989 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S990 Phosphorylation PhosphoSitePlus
S992 Phosphorylation PhosphoSitePlus
S996 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S996 Phosphorylation PhosphoSitePlus
S999 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...35254053, 30379171, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
T1002 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S1003 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...30379171, 32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S1004 O-Glycosylation GlyGen 34846842, 33214551, 28314751, ...35254053, 30379171, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928, 27217568, 29237092
S1021 Phosphorylation PhosphoSitePlus
S1025 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1030 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y64 Phosphorylation HPRD 20068231
S173 Phosphorylation HPRD 19651622, 18491316, 17081983, ...20068231
S175 Phosphorylation HPRD 19651622, 17081983, 20068231
S336 Phosphorylation HPRD 19651622, 20068231, 18452278
S338 Phosphorylation HPRD 19651622, 20068231
S493 Phosphorylation HPRD 17081983
S660 Phosphorylation HPRD 20068231, 18452278
T818 Phosphorylation HPRD 20068231
S821 Phosphorylation HPRD 20068231
S978 Phosphorylation HPRD 18452278
T981 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 Y11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S15 F15 Biomuta [ cosmic ]
Y112 H112 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S187 F187 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S352 P352 Biomuta DOID:263 / kidney cancer [ cosmic ]
S493 L493 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S764 Y764 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T818 P818 Biomuta DOID:263 / kidney cancer [ cosmic ]
S821 F821 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T875 A875 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S878 L878 Biomuta DOID:363 / uterine cancer [ icgc ]
S879 F879 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S881 F881 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S894 Y894 Biomuta DOID:363 / uterine cancer [ icgc ]
S977 F977 Biomuta [ cosmic ]
S990 L990 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1003 L1003 Biomuta DOID:1319 / brain cancer [ icgc ]
S1021 F1021 Biomuta DOID:3571 / liver cancer [ cosmic ]