iPTMnet Report for Q9NPF4 (OSGEP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPF4 / OSGEP_HUMAN
Protein Name tRNA N6-adenosine threonylcarbamoyltransferase
Gene Name Name: OSGEP
Synonyms:GCPL1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NPF4
DAG View
PRO Name tRNA N6-adenosine threonylcarbamoyltransferase (human)
Definition A tRNA N6-adenosine threonylcarbamoyltransferase that is encoded in the genome of human.
Short Label hOSGEP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPF4 (OSGEP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
S88 Phosphorylation IEDB 32387766
T127 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
C230 Methylation IEDB 31844290
S318 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K185 R185 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K189 T189 Biomuta DOID:363 / uterine cancer [ icgc ]
T221 I221 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S318 F318 Biomuta DOID:3571 / liver cancer [ cosmic ]