Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NPD3 / EXOS4_HUMAN
Protein Name Exosome complex component RRP41
Gene Name Name: EXOSC4
Organism Homo sapiens (Human)

DAG View
PRO Name exosome complex component RRP41 (human)
Definition An exosome complex component RRP41 that is encoded in the genome of human.
Short Label hEXOSC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NPD3 (EXOSC4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S61 Phosphorylation PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
R230 Methylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R230 L230 Biomuta DOID:3571 / liver cancer [ icgc ]