iPTMnet Report Q9NPD3 EXOSC4

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NPD3 / EXOS4_HUMAN
Protein Name	Exosome complex component RRP41
Gene Name	Name: EXOSC4 Synonyms:RRP41,SKI6;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NPD3 DAG View
PRO Name	exosome complex component RRP41 (human)
Definition	An exosome complex component RRP41 that is encoded in the genome of human.
Short Label	hEXOSC4
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NPD3 (EXOSC4) as Substrate

Q9NPD3

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	A2	Acetylation		score1	UniProt	19413330, 22814378, 22223895
	S61	Phosphorylation		score1	PhosphoSitePlus
	T83	Phosphorylation		score1	PhosphoSitePlus
	K95	Ubiquitination		score1	PhosphoSitePlus
	S96	Phosphorylation		score1	PhosphoSitePlus
	C158	Methylation		score1	IEDB	31844290
	R230	Methylation		score1	PhosphoSitePlus
	S240	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
R230	Q230	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]