Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NPC3 / CIP1_HUMAN
Protein Name E3 ubiquitin-protein ligase CCNB1IP1
Gene Name Name: CCNB1IP1
Organism Homo sapiens (Human)

DAG View
PRO Name E3 ubiquitin-protein ligase CCNB1IP1 (human)
Definition An E3 ubiquitin-protein ligase CCNB1IP1 that is encoded in the genome of human.
Short Label hCCNB1IP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NPC3 (CCNB1IP1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y125 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S158 Phosphorylation HPRD 18767875
S161 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation HPRD   PhosphoSitePlus 17322306
S180 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
S257 Phosphorylation HPRD 12612082
S259 Phosphorylation HPRD 12612082

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y125 C125 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y125 H125 Biomuta DOID:10534 / stomach cancer [ cosmic, tcga ] DOID:3571 / liver cancer [ icgc ]
K154 N154 Biomuta DOID:363 / uterine cancer [ tcga ]
T221 K221 Biomuta DOID:3571 / liver cancer [ icgc ]