iPTMnet Report for Q9NP72 (RAB18)
Protein Information
| UniProt AC / UniProt ID | Q9NP72 / RAB18_HUMAN |
| Protein Name | Ras-related protein Rab-18 precursor |
| Gene Name | Name: RAB18 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NP72 |
| PRO Name | Ras-related protein Rab-18 (human) |
| Definition | A Ras-related protein Rab-18 that is encoded in the genome of human. |
| Short Label | hRAB18 |
| Category | organism-gene |
Q9NP72 (RAB18) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22223895 | ||
| K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y77 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K138 | Acetylation | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y202 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K123 | R123 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K138 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K138 | I138 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S144 | F144 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K183 | E183 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View