Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NP62 / GCM1_HUMAN
Protein Name Chorion-specific transcription factor GCMa
Gene Name Name: GCM1
Synonyms:GCMA;
Organism Homo sapiens (Human)

PRO ID PR:Q9NP62
DAG View
PRO Name chorion-specific transcription factor GCMa (human)
Definition A chorion-specific transcription factor GCMa that is encoded in the genome of human.
Short Label hGCM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NP62 (GCM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation Q14012 (CAMK1) neXtProt   PhosphoSitePlus   Signor 21791615
T64 O-Glycosylation GlyGen 30379171
S69 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
K156 Sumoylation PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus   RLIMS-P 20855292
S275 Phosphorylation PhosphoSitePlus   RLIMS-P 20855292
S322 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   RLIMS-P 20855292, 19416964
S326 Phosphorylation PhosphoSitePlus
S328 Phosphorylation RLIMS-P 22206674
K367 Acetylation PhosphoSitePlus
S378 Phosphorylation RLIMS-P 22206674
S383 Phosphorylation RLIMS-P 22206674
K406 Acetylation PhosphoSitePlus
K409 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K367 Acetylation PR:Q92793 (hCREBBP) PRO 16166624
K406 Acetylation PR:Q92793 (hCREBBP) PRO 16166624
K409 Acetylation PR:Q92793 (hCREBBP) PRO 16166624


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000028754 (hGCM1/iso:1/Ac:1) acK367,acK406,acK409 PR:Q92793 (hCREBBP) PRO 16166624


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9NP62 (GCM1) S275 Q9BVJ7 (DUSP23) unknown eFIP 20855292


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S47 L47 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S322 N322 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K406 R406 Biomuta DOID:4159 / skin cancer [ cosmic ]