iPTMnet Report for Q9NP60 (IL1RAPL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NP60 / IRPL2_HUMAN
Protein Name X-linked interleukin-1 receptor accessory protein-like 2 precursor
Gene Name Name: IL1RAPL2
Synonyms:IL1R9;
Organism Homo sapiens (Human)

PRO ID PR:Q9NP60
DAG View
PRO Name X-linked interleukin-1 receptor accessory protein-like 2 (human)
Definition An X-linked interleukin-1 receptor accessory protein-like 2 that is encoded in the genome of human.
Short Label hIL1RAPL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NP60 (IL1RAPL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K78 Sumoylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
K170 Acetylation PhosphoSitePlus
S343 Phosphorylation HPRD   PhosphoSitePlus 20230923
Y408 Phosphorylation PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
K543 Acetylation PhosphoSitePlus
K547 Acetylation PhosphoSitePlus
K560 Acetylation PhosphoSitePlus
K561 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 P35 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K170 R170 Biomuta [ cosmic ]
Y456 C456 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S541 C541 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S541 N541 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S541 I541 Biomuta DOID:363 / uterine cancer [ icgc ]
S542 I542 Biomuta DOID:9256 / colorectal cancer [ cosmic ]