iPTMnet Report for Q9NNX1 (TUFT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NNX1 / TUFT1_HUMAN
Protein Name Tuftelin
Gene Name Name: TUFT1
Organism Homo sapiens (Human)

PRO ID PR:Q9NNX1
DAG View
PRO Name tuftelin (human)
Definition A tuftelin that is encoded in the genome of human.
Short Label hTUFT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NNX1 (TUFT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T50 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
K79 Sumoylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S378 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K115 M115 Biomuta DOID:3571 / liver cancer [ cosmic ]
S131 C131 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S370 I370 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]