iPTMnet Report Q9HDC5 JPH1

Protein Information

UniProt AC / UniProt ID	Q9HDC5 / JPH1_HUMAN
Protein Name	Junctophilin-1
Gene Name	Name: JPH1 Synonyms:JP1;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9HDC5 DAG View
PRO Name	junctophilin-1 (human)
Definition	A junctophilin-1 that is encoded in the genome of human.
Short Label	hJPH1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9HDC5 (JPH1) as Substrate

Q9HDC5

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position K77 K91 T153 S157 T161 S162 S165 S185 T189 K208 S216 S220 S238 S246 S296 K373 S413 Y417 K425 T448 S452 T460 T461 S465 S469 S473 S475 S478 S479 S548 Y550 Y553 Y554 S573 S577 S585 S590 S592 K611 S625	PTM Type Select all Acetylation O-Glycosylation Phosphorylation Ubiquitination	Score Select all 0 1 2	Source Select all GlyGen HPRD PhosphoSitePlus UniProt phospho.ELM	PMID
K77	Ubiquitination	score1	PhosphoSitePlus
K91	Ubiquitination	score1	PhosphoSitePlus
T153	Phosphorylation	score1	PhosphoSitePlus
S157	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	18669648
T161	Phosphorylation	score1	PhosphoSitePlus
S162	Phosphorylation	score2	HPRD PhosphoSitePlus	19691289
S165	Phosphorylation	score1	PhosphoSitePlus
S185	Phosphorylation	score1	PhosphoSitePlus
T189	Phosphorylation	score1	PhosphoSitePlus
K208	Acetylation	score1	PhosphoSitePlus
S216	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	21406692, 23186163, 18669648, ...20068231
S220	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	18669648, 21406692, 20068231
S238	Phosphorylation	score1	PhosphoSitePlus
S246	Phosphorylation	score1	PhosphoSitePlus
S296	O-Glycosylation	score1	GlyGen	30620550
K373	Ubiquitination	score1	PhosphoSitePlus
S413	Phosphorylation	score1	PhosphoSitePlus
Y417	Phosphorylation	score1	PhosphoSitePlus
K425	Ubiquitination	score1	PhosphoSitePlus
T448	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	23186163, 17081983, 18767875, ...19651622, 18669648, 20068231
S452	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	17081983, 18767875, 19651622, ...18669648, 20068231
T460	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus	19413330, 18669648
T461	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19413330, 18669648, 23186163
S465	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19413330, 18669648, 23186163
S469	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19413330, 18669648, 23186163
S473	Phosphorylation	score0	HPRD	17081983
S475	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19651622, 21406692, 17081983, ...20068231
S478	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus	17081983, 20068231
S479	Phosphorylation	score2	HPRD PhosphoSitePlus	19651622, 17081983, 20068231
S548	Phosphorylation	score1	PhosphoSitePlus
Y550	Phosphorylation	score1	PhosphoSitePlus
Y553	Phosphorylation	score1	PhosphoSitePlus
Y554	Phosphorylation	score1	PhosphoSitePlus
S573	Phosphorylation	score0	HPRD	17081983
S577	Phosphorylation	score0	HPRD	17081983
S585	Phosphorylation	score0	HPRD	17081983
S590	Phosphorylation	score1	PhosphoSitePlus
S592	Phosphorylation	score2	HPRD PhosphoSitePlus	17081983
K611	Ubiquitination	score1	PhosphoSitePlus
S625	Phosphorylation	score2	HPRD PhosphoSitePlus	19413330

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position T153 T161 S162 S216 T460 S548 S573 S585 S592	Variant Select all A460 C548 F216 F548 F585 F592 L162 M153 M460 P573 S161 Y573	Source Select all Biomuta	Disease [Sample source] Select all DOID:11054 / urinary bladder cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T153	M153	Biomuta	DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T161	S161	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S162	L162	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ icgc ]
S216	F216	Biomuta	[ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T460	M460	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T460	A460	Biomuta	DOID:1612 / breast cancer [ cosmic, icgc ]
S548	F548	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S548	C548	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S573	P573	Biomuta	DOID:1319 / brain cancer [ cosmic ]
S573	Y573	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S585	F585	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
S592	F592	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9HDC5 (JPH1)

Protein Information

Interactive Sequence View

Q9HDC5 (JPH1) as Substrate

PTM sites affected in variants