iPTMnet Report for Q9HD20 (ATP13A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HD20 / AT131_HUMAN
Protein Name Endoplasmic reticulum transmembrane helix translocase
Gene Name Name: ATP13A1
Synonyms:ATP13A;ORFNames:CGI-152;
Organism Homo sapiens (Human)

PRO ID PR:Q9HD20
DAG View
PRO Name endoplasmic reticulum transmembrane helix translocase (human)
Definition An endoplasmic reticulum transmembrane helix translocase that is encoded in the genome of human.
Short Label hATP13A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HD20 (ATP13A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
C108 Methylation IEDB 31844290
K143 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
K220 Acetylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
R371 Methylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
Y413 Phosphorylation PhosphoSitePlus
N420 N-Glycosylation GlyGen   UniProt 16335952
K425 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus
T567 Phosphorylation PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
S638 O-Glycosylation GlyGen 29351928
S644 Phosphorylation PhosphoSitePlus
T645 Phosphorylation PhosphoSitePlus
Y649 Phosphorylation PhosphoSitePlus
C667 Methylation IEDB 31844290
Y671 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
Y690 Phosphorylation PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
S722 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
K778 Acetylation PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
T850 Phosphorylation PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
Y857 Phosphorylation PhosphoSitePlus
S899 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...24275569
T901 Phosphorylation PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus   UniProt 23186163
S911 Phosphorylation PhosphoSitePlus
T913 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S945 Phosphorylation PhosphoSitePlus
K950 Ubiquitination PhosphoSitePlus
K963 Ubiquitination PhosphoSitePlus
K1038 Ubiquitination PhosphoSitePlus
K1083 Ubiquitination PhosphoSitePlus
Y1091 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S722 Phosphorylation HPRD 20068231
S899 Phosphorylation HPRD 17081983, 19007248, 19691289, ...19651622, 18669648, 20068231, 20068230
T901 Phosphorylation HPRD 19007248
S935 Phosphorylation HPRD 19651622, 18077418, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K186 N186 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K220 R220 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K308 T308 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R371 Q371 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R371 W371 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T603 N603 Biomuta DOID:1319 / brain cancer [ cosmic ]
S644 C644 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T645 I645 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S679 F679 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y690 N690 Biomuta DOID:4159 / skin cancer [ cosmic ]
S722 F722 Biomuta DOID:363 / uterine cancer [ icgc ]
K730 N730 Biomuta DOID:363 / uterine cancer [ icgc ]
Y857 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S905 I905 Biomuta DOID:1324 / lung cancer [ cosmic ]
S945 I945 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1083 R1083 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]