iPTMnet Report for Q9HCX4 (TRPC7)
Protein Information
| UniProt AC / UniProt ID | Q9HCX4 / TRPC7_HUMAN |
| Protein Name | Short transient receptor potential channel 7 |
| Gene Name | Name: TRPC7 Synonyms:TRP7; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HCX4 |
| PRO Name | short transient receptor potential channel 7 (human) |
| Definition | A short transient receptor potential cation channel TRPC7 that is encoded in the genome of human. |
| Short Label | hTRPC7 |
| Category | organism-gene |
DAG ViewQ9HCX4 (TRPC7) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T15 | Phosphorylation | Q13976 (PRKG1) | score3 | neXtProt PhosphoSitePlus UniProt | 21402151 | |
| T16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T415 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y424 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S551 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S714 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S775 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T778 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S817 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y821 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoform PPIs
|
Protein 1 | Relation | Protein 2 | Source | PMID |
|---|---|---|---|---|---|
| PR:Q9HCX4 (hTRPC7) | Interaction | PR:P20591 (hMX1) | PRO | 15757897 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T16 | M16 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S211 | F211 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S215 | L215 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S215 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S217 | L217 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| Y424 | S424 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T525 | N525 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y526 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S551 | G551 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
