iPTMnet Report for Q9HCU5 (PREB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCU5 / PREB_HUMAN
Protein Name Prolactin regulatory element-binding protein
Gene Name Name: PREB
Synonyms:SEC12;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCU5
DAG View
PRO Name prolactin regulatory element-binding protein (human)
Definition A prolactin regulatory element-binding protein that is encoded in the genome of human.
Short Label hPREB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCU5 (PREB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y10 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
C90 Methylation IEDB 31844290
K104 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
C280 Methylation IEDB 31844290
T295 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y10 H10 Biomuta DOID:1319 / brain cancer [ cosmic ]
K127 T127 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K224 N224 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T347 M347 Biomuta DOID:9256 / colorectal cancer [ cosmic ]