iPTMnet Report for Q9HCS7 (XAB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCS7 / SYF1_HUMAN
Protein Name Pre-mRNA-splicing factor SYF1
Gene Name Name: XAB2
Synonyms:HCNP,KIAA1177,SYF1;ORFNames:PP3898;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCS7
DAG View
PRO Name pre-mRNA-splicing factor SYF1 (human)
Definition A pre-mRNA-splicing factor SYF1 that is encoded in the genome of human.
Short Label hXAB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCS7 (XAB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
C66 S-Nitrosylation dbSNO 24105792
K69 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K420 Acetylation PhosphoSitePlus   UniProt 19608861
K420 Ubiquitination PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
Y469 Phosphorylation PhosphoSitePlus
R479 Methylation PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
T499 Phosphorylation HPRD   PhosphoSitePlus 18491316
K539 Ubiquitination PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
C668 Methylation IEDB 31844290
K677 Ubiquitination PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
K708 Ubiquitination PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
K770 Ubiquitination PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
S851 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K853 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K62 R62 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K212 E212 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S315 L315 Biomuta DOID:4159 / skin cancer [ cosmic ]
K420 Q420 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R479 H479 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K482 E482 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T706 M706 Biomuta DOID:9256 / colorectal cancer [ cosmic ]