iPTMnet Report for Q9HCN3 (PGAP6)
Protein Information
| UniProt AC / UniProt ID | Q9HCN3 / PGAP6_HUMAN |
| Protein Name | Post-GPI attachment to proteins factor 6 precursor |
| Gene Name | Name: PGAP6 Synonyms:TMEM6,TMEM8,TMEM8A; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HCN3 |
| PRO Name | post-GPI attachment to proteins factor 6 (human) |
| Definition | A transmembrane protein 8 that is encoded in the genome of human. |
| Short Label | hPGAP6 |
| Category | organism-gene |
Q9HCN3 (PGAP6) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N232 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S330 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| Y354 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S380 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N535 | N-Glycosylation | score1 | GlyGen | 29741879 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K169 | T169 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S330 | F330 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| T357 | M357 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T382 | M382 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
DAG View