iPTMnet Report for Q9HCM9 (TRIM39)
Protein Information
UniProt AC / UniProt ID | Q9HCM9 / TRI39_HUMAN |
Protein Name | E3 ubiquitin-protein ligase TRIM39 |
Gene Name | Name: TRIM39 Synonyms:RNF23,TFP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HCM9 |
PRO Name | E3 ubiquitin-protein ligase TRIM39 (human) |
Definition | An E3 ubiquitin-protein ligase TRIM39 that is encoded in the genome of human. |
Short Label | hTRIM39 |
Category | organism-gene |
Q9HCM9 (TRIM39) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K98 | Acetylation | score1 | PhosphoSitePlus | |||
T147 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y150 | Phosphorylation | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
T280 | Phosphorylation | score1 | PhosphoSitePlus | |||
T385 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y439 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 16094384 | ||
T468 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y472 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K260 | Acetylation | score1 | PhosphoSitePlus | |||
K268 | Acetylation | score1 | PhosphoSitePlus | |||
K273 | Acetylation | score1 | PhosphoSitePlus | |||
Y409 | Phosphorylation | score0 | HPRD | 16094384 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K98 | R98 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T280 | M280 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T468 | A468 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |