iPTMnet Report for Q9HCM2 (PLXNA4)
Protein Information
| UniProt AC / UniProt ID | Q9HCM2 / PLXA4_HUMAN |
| Protein Name | Plexin-A4 precursor |
| Gene Name | Name: PLXNA4 Synonyms:KIAA1550,PLXNA4A,PLXNA4B;ORFNames:UNQ2820/PRO34003; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HCM2 |
| PRO Name | plexin-A4 (human) |
| Definition | A plexin-A4 that is encoded in the genome of human. |
| Short Label | hPLXNA4 |
| Category | organism-gene |
Q9HCM2 (PLXNA4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| Y159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K344 | Acetylation | score1 | PhosphoSitePlus | |||
| S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S946 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| S1002 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1003 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1009 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1235 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1350 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| S1419 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1424 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1483 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1489 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1497 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1543 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1605 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1627 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1628 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1633 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1670 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1685 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1791 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1797 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T461 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S462 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T466 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048825 (hPLXNA4/SigPep-/PhosTyr+) | p | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S488 | T488 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S488 | F488 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S1002 | F1002 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y1003 | C1003 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| S1235 | G1235 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S1543 | F1543 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S1543 | Y1543 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y1627 | F1627 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S1630 | I1630 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| S1633 | I1633 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S1633 | N1633 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K1791 | N1791 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View