iPTMnet Report for Q9HCM1 (RESF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCM1 / RESF1_HUMAN
Protein Name Retroelement silencing factor 1
Gene Name Name: RESF1
Synonyms:C12orf35,KIAA1551;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCM1
DAG View
PRO Name retroelement silencing factor 1 (human)
Definition A retroelement silencing factor 1 that is encoded in the genome of human.
Short Label hRESF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCM1 (RESF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S221 Phosphorylation IEDB   PhosphoSitePlus   UniProt 23186163, 33936100
K233 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
T698 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
T701 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
K707 Ubiquitination PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
K777 Ubiquitination PhosphoSitePlus
K793 Ubiquitination PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
K830 Ubiquitination PhosphoSitePlus
K837 Ubiquitination PhosphoSitePlus
K839 Ubiquitination PhosphoSitePlus
S868 Phosphorylation PhosphoSitePlus
K919 Ubiquitination PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
K950 Ubiquitination PhosphoSitePlus
K956 Ubiquitination PhosphoSitePlus
K958 Ubiquitination PhosphoSitePlus
K968 Ubiquitination PhosphoSitePlus
K974 Ubiquitination PhosphoSitePlus
K995 Ubiquitination PhosphoSitePlus
K1045 Ubiquitination PhosphoSitePlus
S1196 Phosphorylation PhosphoSitePlus
S1197 Phosphorylation PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus
S1208 Phosphorylation PhosphoSitePlus
T1227 Phosphorylation PhosphoSitePlus
K1232 Ubiquitination PhosphoSitePlus
K1239 Ubiquitination PhosphoSitePlus
T1240 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1262 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
K1282 Ubiquitination PhosphoSitePlus
K1285 Ubiquitination PhosphoSitePlus
K1293 Ubiquitination PhosphoSitePlus
S1313 Phosphorylation PhosphoSitePlus
Y1314 Phosphorylation PhosphoSitePlus
T1328 Phosphorylation PhosphoSitePlus
S1356 Phosphorylation HPRD   PhosphoSitePlus 19651622
S1358 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 23186163, ...19664995
K1367 Ubiquitination PhosphoSitePlus
S1400 Phosphorylation PhosphoSitePlus
T1404 Phosphorylation PhosphoSitePlus
K1406 Ubiquitination PhosphoSitePlus
S1426 Phosphorylation PhosphoSitePlus
K1429 Methylation PhosphoSitePlus
S1460 Phosphorylation PhosphoSitePlus
K1506 Ubiquitination PhosphoSitePlus
K1520 Ubiquitination PhosphoSitePlus
K1528 Ubiquitination PhosphoSitePlus
K1552 Acetylation PhosphoSitePlus
K1575 Ubiquitination PhosphoSitePlus
K1624 Ubiquitination PhosphoSitePlus
K1629 Ubiquitination PhosphoSitePlus
K1644 Ubiquitination PhosphoSitePlus
K1661 Ubiquitination PhosphoSitePlus
K1675 Ubiquitination PhosphoSitePlus
K1704 Acetylation PhosphoSitePlus
S1706 Phosphorylation PhosphoSitePlus
S1708 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1730 Acetylation PhosphoSitePlus
Y1733 Phosphorylation PhosphoSitePlus
S1738 Phosphorylation PhosphoSitePlus
S1740 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1743 Phosphorylation PhosphoSitePlus
S1744 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K233 R233 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K275 T275 Biomuta DOID:363 / uterine cancer [ icgc ]
S302 F302 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S352 G352 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
K371 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K480 E480 Biomuta DOID:2998 / testicular cancer [ cosmic ]
K512 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K630 N630 Biomuta DOID:1324 / lung cancer [ cosmic ]
T634 I634 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K663 E663 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K809 N809 Biomuta DOID:363 / uterine cancer [ icgc ]
K815 N815 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K958 N958 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K958 T958 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1197 Y1197 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1208 C1208 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S1266 R1266 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1285 T1285 Biomuta DOID:363 / uterine cancer [ icgc ]
K1293 R1293 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1313 F1313 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1313 Y1313 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T1328 A1328 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1356 T1356 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1400 N1400 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1429 N1429 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K1520 E1520 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1552 M1552 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1575 N1575 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y1733 F1733 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1738 I1738 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1744 R1744 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]