iPTMnet Report for Q9HCK1 (ZDBF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCK1 / ZDBF2_HUMAN
Protein Name DBF4-type zinc finger-containing protein 2
Gene Name Name: ZDBF2
Synonyms:KIAA1571;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCK1
DAG View
PRO Name DBF4-type zinc finger-containing protein 2 (human)
Definition A DBF4-type zinc finger-containing protein 2 that is encoded in the genome of human.
Short Label hZDBF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCK1 (ZDBF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T40 O-Glycosylation GlyGen 23301498, 30379171, 29237092
S41 O-Glycosylation GlyGen 23301498, 30379171, 29237092
S124 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
S266 O-Glycosylation GlyGen 23301498, 30379171, 29237092
K287 Methylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation HPRD 18669648
T462 Phosphorylation HPRD 18669648
S465 Phosphorylation HPRD 18669648
Y531 Phosphorylation HPRD 17081983
S533 Phosphorylation HPRD 17081983
S534 Phosphorylation HPRD 17081983
S535 Phosphorylation HPRD 17081983
S536 Phosphorylation HPRD 17081983
S539 Phosphorylation HPRD   UniProt 17081983
S548 Phosphorylation PhosphoSitePlus
T560 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
K898 Acetylation PhosphoSitePlus
S957 Phosphorylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
Y1027 Phosphorylation PhosphoSitePlus
K1079 Acetylation PhosphoSitePlus
S1197 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
S1574 Phosphorylation PhosphoSitePlus
K1701 Acetylation PhosphoSitePlus
S1706 Phosphorylation PhosphoSitePlus
S1778 Phosphorylation PhosphoSitePlus
K1842 Ubiquitination PhosphoSitePlus
S1870 O-Glycosylation GlyGen 23301498, 30379171, 29237092
Y1953 Phosphorylation PhosphoSitePlus
K1957 Methylation PhosphoSitePlus
S1995 Phosphorylation PhosphoSitePlus
T1997 Phosphorylation PhosphoSitePlus
S2013 Phosphorylation PhosphoSitePlus
S2014 Phosphorylation PhosphoSitePlus
K2133 Ubiquitination PhosphoSitePlus
K2166 Acetylation PhosphoSitePlus
K2173 Acetylation PhosphoSitePlus
Y2195 Phosphorylation PhosphoSitePlus
Y2226 Phosphorylation PhosphoSitePlus
Y2230 Phosphorylation PhosphoSitePlus
S2240 Phosphorylation PhosphoSitePlus
S2330 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K287 Q287 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K287 E287 Biomuta DOID:363 / uterine cancer [ icgc ]
S370 C370 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S370 F370 Biomuta DOID:4159 / skin cancer [ cosmic ]
S413 Y413 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S465 F465 Biomuta DOID:4159 / skin cancer [ cosmic ]
S465 C465 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S534 R534 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S536 Y536 Biomuta DOID:1324 / lung cancer [ cosmic ]
S548 L548 Biomuta DOID:4159 / skin cancer [ cosmic ]
S548 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S620 T620 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S957 N957 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1200 R1200 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1701 M1701 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1778 F1778 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1870 L1870 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T1997 I1997 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S2013 F2013 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2013 Y2013 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y2195 C2195 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y2230 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S2240 F2240 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S2240 C2240 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]