iPTMnet Report for Q9HCJ2 (LRRC4C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCJ2 / LRC4C_HUMAN
Protein Name Leucine-rich repeat-containing protein 4C precursor
Gene Name Name: LRRC4C
Synonyms:KIAA1580,NGL1;ORFNames:UNQ292/PRO331;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCJ2
DAG View
PRO Name leucine-rich repeat-containing protein 4C (human)
Definition A netrin-G1 ligand that is encoded in the genome of human.
Short Label hLRRC4C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCJ2 (LRRC4C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T46 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K317 Sumoylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Y548 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
S631 Phosphorylation O76039 (CDKL5) PhosphoSitePlus   RLIMS-P   Signor 22922712


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T46 N46 Biomuta DOID:1324 / lung cancer [ cosmic ]
S54 R54 Biomuta DOID:1324 / lung cancer [ cosmic ]
K317 N317 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T324 A324 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T610 S610 Biomuta DOID:2531 / hematologic cancer [ cosmic ]