iPTMnet Report for Q9HCJ0 (TNRC6C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCJ0 / TNR6C_HUMAN
Protein Name Trinucleotide repeat-containing gene 6C protein
Gene Name Name: TNRC6C
Synonyms:KIAA1582;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCJ0
DAG View
PRO Name trinucleotide repeat-containing gene 6C protein (human)
Definition A trinucleotide repeat-containing gene 6C protein that is encoded in the genome of human.
Short Label hTNRC6C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCJ0 (TNRC6C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R313 Methylation PhosphoSitePlus   UniProt 24129315
S315 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
K455 Acetylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S532 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S547 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 32938750, 28411811, 29351928, 35132862, 35254053
S554 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus
S628 Phosphorylation PhosphoSitePlus
T633 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
T645 Phosphorylation PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T777 Phosphorylation PhosphoSitePlus   UniProt 24275569
S790 Phosphorylation PhosphoSitePlus
K798 Acetylation PhosphoSitePlus
K812 Acetylation PhosphoSitePlus
S872 Phosphorylation PhosphoSitePlus
K978 Acetylation PhosphoSitePlus
S1011 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1036 Phosphorylation PhosphoSitePlus
S1038 Phosphorylation PhosphoSitePlus
R1088 Methylation PhosphoSitePlus
R1109 Methylation PhosphoSitePlus
T1244 Phosphorylation PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus
S1314 Phosphorylation PhosphoSitePlus
S1358 Phosphorylation PhosphoSitePlus
K1437 Acetylation PhosphoSitePlus
S1447 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1451 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
T1453 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1456 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1528 Phosphorylation PhosphoSitePlus
T1529 Phosphorylation PhosphoSitePlus
T1532 Phosphorylation PhosphoSitePlus
T1602 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1603 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 32938750, 28411811, 29351928, 35132862, 35254053
S1604 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1607 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1621 Phosphorylation PhosphoSitePlus
T1677 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
T1678 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...30397120, 28411811, 29351928, 35132862, 35254053
S1689 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S626 Phosphorylation HPRD 20068231
T633 Phosphorylation HPRD 20068231
T634 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S790 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S547 N547 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S579 F579 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S588 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T634 M634 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
T645 K645 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T647 I647 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1088 G1088 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1088 S1088 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1109 C1109 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S1447 P1447 Biomuta DOID:363 / uterine cancer [ icgc ]
T1453 K1453 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T1532 I1532 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1689 F1689 Biomuta DOID:4159 / skin cancer [ cosmic ]