Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCH5 / SYTL2_HUMAN
Protein Name Synaptotagmin-like protein 2
Gene Name Name: SYTL2
Synonyms:KIAA1597,SGA72M,SLP2,SLP2A;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCH5
DAG View
PRO Name synaptotagmin-like protein 2 (human)
Definition A synaptotagmin-like protein 2 that is encoded in the genome of human.
Short Label hSYTL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCH5 (SYTL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T245 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
Y386 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
Y400 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
Y668 Phosphorylation PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
T691 Phosphorylation PhosphoSitePlus
Y696 Phosphorylation PhosphoSitePlus
Y890 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S244 Phosphorylation HPRD 18452278
T245 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
T38 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
Y142 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
Y549 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
T697 Phosphorylation PhosphoSitePlus
T713 Phosphorylation PhosphoSitePlus
S773 Phosphorylation PhosphoSitePlus
K777 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S198 L198 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
Y386 * Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:1115 / sarcoma [ tcga ]
S390 L390 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S437 * Biomuta DOID:3571 / liver cancer [ icgc ]
S437 L437 Biomuta DOID:1324 / lung cancer [ tcga ]
S460 T460 Biomuta DOID:1324 / lung cancer [ tcga ]
S480 I480 Biomuta DOID:363 / uterine cancer [ tcga ]
S488 L488 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S511 I511 Biomuta DOID:1324 / lung cancer [ tcga ]
Y672 C672 Biomuta DOID:363 / uterine cancer [ icgc, tcga ] DOID:3371 / chondrosarcoma [ cosmic ]
K690 N690 Biomuta DOID:10534 / stomach cancer [ cosmic ]