Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCG7 / GBA2_HUMAN
Protein Name Non-lysosomal glucosylceramidase
Gene Name Name: GBA2
Synonyms:KIAA1605;ORFNames:AD035;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCG7
DAG View
PRO Name non-lysosomal glucosylceramidase (human)
Definition A non-lysosomal glucosylceramidase that is encoded in the genome of human.
Short Label hGBA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCG7 (GBA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
Y576 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K761 Ubiquitination PhosphoSitePlus
K904 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S47 R47 Biomuta DOID:3277 / thymus cancer [ tcga ]
K904 R904 Biomuta DOID:3963 / thyroid carcinoma [ tcga ]