iPTMnet Report for Q9HCG7 (GBA2)
Protein Information
| UniProt AC / UniProt ID | Q9HCG7 / GBA2_HUMAN |
| Protein Name | Non-lysosomal glucosylceramidase |
| Gene Name | Name: GBA2 Synonyms:KIAA1605;ORFNames:AD035; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HCG7 |
| PRO Name | non-lysosomal glucosylceramidase (human) |
| Definition | A non-lysosomal glucosylceramidase that is encoded in the genome of human. |
| Short Label | hGBA2 |
| Category | organism-gene |
DAG ViewQ9HCG7 (GBA2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T11 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S212 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y576 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S579 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K586 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K761 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K904 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y576 | * | Biomuta | [ cosmic ] | |
| K904 | R904 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
