Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCD5 / NCOA5_HUMAN
Protein Name Nuclear receptor coactivator 5
Gene Name Name: NCOA5
Synonyms:KIAA1637;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCD5
DAG View
PRO Name nuclear receptor coactivator 5 (human)
Definition A nuclear receptor coactivator 5 that is encoded in the genome of human.
Short Label hNCOA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCD5 (NCOA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 21406692, 20068231
T3 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19651622, 20068231
S6 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231
S9 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 19651622, 20068231
T11 Phosphorylation HPRD   PhosphoSitePlus 17081983
R13 Methylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus   UniProt 23186163
S24 Phosphorylation PhosphoSitePlus   UniProt 23186163
S29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 23186163, 17081983, ...20068231
S34 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 23186163, 17081983, ...20068231
S51 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y107 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus   UniProt 23186163
S126 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
Y127 Phosphorylation HPRD   phospho.ELM 17081983
Y136 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y144 Phosphorylation PhosphoSitePlus
S151 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S162 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
Y184 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T267 Phosphorylation HPRD 20068231
T274 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 20068231, 18220336
K362 Ubiquitination PhosphoSitePlus
S377 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17287340, 20068231
S378 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T379 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163, ...20068231
S381 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...18669648, 24275569, 19690332, 20068231
S387 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
T394 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
S404 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
T418 Phosphorylation PhosphoSitePlus
T420 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
S477 Phosphorylation PhosphoSitePlus
R500 Methylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
R515 Methylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
T546 Phosphorylation HPRD 20068231
T562 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 I1 Biomuta DOID:1324 / lung cancer [ tcga ]
T3 M3 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T3 A3 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S143 C143 Biomuta DOID:4362 / cervical cancer [ tcga ]
T379 I379 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S395 L395 Biomuta DOID:363 / uterine cancer [ tcga ]
T420 S420 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]
T546 I546 Biomuta DOID:363 / uterine cancer [ tcga ]