iPTMnet Report for Q9HCB6 (SPON1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCB6 / SPON1_HUMAN
Protein Name Spondin-1 precursor
Gene Name Name: SPON1
Synonyms:KIAA0762,VSGP;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCB6
DAG View
PRO Name spondin-1 (human)
Definition A spondin-1 that is encoded in the genome of human.
Short Label hSPON1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCB6 (SPON1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 O-Glycosylation GlyGen 29237092
S11 O-Glycosylation GlyGen 29237092
S40 Phosphorylation PhosphoSitePlus
Y43 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
Y78 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
T192 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
N214 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...21569239
S276 Phosphorylation PhosphoSitePlus
W448 C-Glycosylation GlyGen   UniProt 12096136
W451 C-Glycosylation GlyGen   UniProt 12096136
W507 C-Glycosylation GlyGen   UniProt 12096136
W510 C-Glycosylation GlyGen   UniProt 12096136
W564 C-Glycosylation GlyGen   UniProt 12096136
W620 C-Glycosylation GlyGen   UniProt 12096136
W623 C-Glycosylation GlyGen   UniProt 12096136
W674 C-Glycosylation GlyGen   UniProt 12096136
S725 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S40 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
W448 * Biomuta DOID:4159 / skin cancer [ cosmic ]
W620 L620 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S725 F725 Biomuta DOID:4159 / skin cancer [ cosmic ]
S747 T747 Biomuta DOID:9256 / colorectal cancer [ cosmic ]