iPTMnet Report for Q9HC84 (MUC5B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HC84 / MUC5B_HUMAN
Protein Name Mucin-5B precursor
Gene Name Name: MUC5B
Synonyms:MUC5;
Organism Homo sapiens (Human)

PRO ID PR:Q9HC84
DAG View
PRO Name mucin-5B (human)
Definition A mucin-5B that is encoded in the genome of human.
Short Label hMUC5B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HC84 (MUC5B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S54 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
N145 N-Glycosylation GlyGen   UniProt 34089345, 29741879, 16740002
Y159 Phosphorylation PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
N254 N-Glycosylation GlyGen   UniProt 29741879, 16740002
T472 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
T490 Phosphorylation PhosphoSitePlus
N805 N-Glycosylation GlyGen 29741879
S1003 Phosphorylation PhosphoSitePlus
K1056 Acetylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus
N1556 N-Glycosylation GlyGen   UniProt 29741879, 16740002
T1647 Phosphorylation PhosphoSitePlus
N1774 N-Glycosylation GlyGen 34089345, 29741879
T1775 Phosphorylation PhosphoSitePlus
T1911 Phosphorylation PhosphoSitePlus
T1912 Phosphorylation PhosphoSitePlus
T1913 Phosphorylation PhosphoSitePlus
T1915 Phosphorylation PhosphoSitePlus
T1916 Phosphorylation PhosphoSitePlus
S1956 Phosphorylation PhosphoSitePlus
S1957 Phosphorylation PhosphoSitePlus
T2033 Phosphorylation PhosphoSitePlus
S2035 Phosphorylation PhosphoSitePlus
T2038 Phosphorylation PhosphoSitePlus
S2041 Phosphorylation PhosphoSitePlus
T2049 Phosphorylation PhosphoSitePlus
S2064 Phosphorylation PhosphoSitePlus
S2066 Phosphorylation PhosphoSitePlus
T2081 Phosphorylation PhosphoSitePlus
S2201 O-Glycosylation PhosphoSitePlus
S2205 O-Glycosylation PhosphoSitePlus
S2205 Phosphorylation PhosphoSitePlus
S2206 O-Glycosylation PhosphoSitePlus
T2209 O-Glycosylation PhosphoSitePlus
T2282 Phosphorylation PhosphoSitePlus
T2283 Phosphorylation PhosphoSitePlus
T2285 Phosphorylation PhosphoSitePlus
T2291 Phosphorylation PhosphoSitePlus
K2395 Acetylation PhosphoSitePlus
T2590 Phosphorylation PhosphoSitePlus
S2592 Phosphorylation PhosphoSitePlus
T2595 Phosphorylation PhosphoSitePlus
S2598 Phosphorylation PhosphoSitePlus
T2606 Phosphorylation PhosphoSitePlus
S2758 O-Glycosylation PhosphoSitePlus
S2760 O-Glycosylation PhosphoSitePlus
S2762 O-Glycosylation PhosphoSitePlus
S2763 O-Glycosylation PhosphoSitePlus
T2766 O-Glycosylation PhosphoSitePlus
T2839 Phosphorylation PhosphoSitePlus
T2840 Phosphorylation PhosphoSitePlus
T2842 Phosphorylation PhosphoSitePlus
S2846 Phosphorylation PhosphoSitePlus
T2848 Phosphorylation PhosphoSitePlus
K2952 Acetylation PhosphoSitePlus
T3001 Phosphorylation PhosphoSitePlus
S3014 Phosphorylation PhosphoSitePlus
T3030 Phosphorylation PhosphoSitePlus
S3036 Phosphorylation PhosphoSitePlus
S3041 Phosphorylation PhosphoSitePlus
S3042 Phosphorylation PhosphoSitePlus
S3043 Phosphorylation PhosphoSitePlus
S3044 Phosphorylation PhosphoSitePlus
T3059 Phosphorylation PhosphoSitePlus
S3061 Phosphorylation PhosphoSitePlus
S3207 Phosphorylation PhosphoSitePlus
S3213 Phosphorylation PhosphoSitePlus
S3214 Phosphorylation PhosphoSitePlus
T3290 Phosphorylation PhosphoSitePlus
S3292 Phosphorylation PhosphoSitePlus
T3295 Phosphorylation PhosphoSitePlus
S3298 Phosphorylation PhosphoSitePlus
T3306 Phosphorylation PhosphoSitePlus
S3321 Phosphorylation PhosphoSitePlus
S3323 Phosphorylation PhosphoSitePlus
T3338 Phosphorylation PhosphoSitePlus
S3458 O-Glycosylation PhosphoSitePlus
S3462 O-Glycosylation PhosphoSitePlus
S3462 Phosphorylation PhosphoSitePlus
S3463 O-Glycosylation PhosphoSitePlus
T3466 O-Glycosylation PhosphoSitePlus
S3524 Phosphorylation PhosphoSitePlus
T3528 Phosphorylation PhosphoSitePlus
T3536 Phosphorylation PhosphoSitePlus
T3548 Phosphorylation PhosphoSitePlus
K3652 Acetylation PhosphoSitePlus
T3813 Phosphorylation PhosphoSitePlus
T3847 Phosphorylation PhosphoSitePlus
S3849 Phosphorylation PhosphoSitePlus
T3852 Phosphorylation PhosphoSitePlus
S3855 Phosphorylation PhosphoSitePlus
T3863 Phosphorylation PhosphoSitePlus
S4015 O-Glycosylation PhosphoSitePlus
S4017 O-Glycosylation PhosphoSitePlus
S4019 O-Glycosylation PhosphoSitePlus
S4020 O-Glycosylation PhosphoSitePlus
T4023 O-Glycosylation PhosphoSitePlus
T4096 Phosphorylation PhosphoSitePlus
T4097 Phosphorylation PhosphoSitePlus
T4099 Phosphorylation PhosphoSitePlus
T4105 Phosphorylation PhosphoSitePlus
K4209 Acetylation PhosphoSitePlus
T4283 Phosphorylation PhosphoSitePlus
S4284 Phosphorylation PhosphoSitePlus
T4288 Phosphorylation PhosphoSitePlus
S4299 Phosphorylation PhosphoSitePlus
S4301 Phosphorylation PhosphoSitePlus
T4307 Phosphorylation PhosphoSitePlus
T4316 Phosphorylation PhosphoSitePlus
S4318 Phosphorylation PhosphoSitePlus
T4347 Phosphorylation PhosphoSitePlus
S4349 Phosphorylation PhosphoSitePlus
T4356 Phosphorylation PhosphoSitePlus
S4498 Phosphorylation PhosphoSitePlus
S4499 Phosphorylation PhosphoSitePlus
S4500 Phosphorylation PhosphoSitePlus
T4516 Phosphorylation PhosphoSitePlus
S4527 Phosphorylation PhosphoSitePlus
T4575 Phosphorylation PhosphoSitePlus
S4577 Phosphorylation PhosphoSitePlus
T4580 Phosphorylation PhosphoSitePlus
S4583 Phosphorylation PhosphoSitePlus
T4591 Phosphorylation PhosphoSitePlus
T4743 Phosphorylation PhosphoSitePlus
S4745 Phosphorylation PhosphoSitePlus
N4804 N-Glycosylation GlyGen 34089345, 29741879
N4960 N-Glycosylation GlyGen   UniProt 34089345, 29741879, 16740002
N5017 N-Glycosylation GlyGen   UniProt 16740002
N5024 N-Glycosylation GlyGen   UniProt 16740002
N5046 N-Glycosylation GlyGen   UniProt 34089345, 29741879, 16740002
N5096 N-Glycosylation GlyGen   UniProt 29741879, 16740002
N5111 N-Glycosylation GlyGen   UniProt 16740002
S5142 Phosphorylation PhosphoSitePlus
N5215 N-Glycosylation GlyGen   UniProt 16740002


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y172 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
T490 M490 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
N805 T805 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1482 L1482 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
N1774 D1774 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1913 K1913 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1916 M1916 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S1956 F1956 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2066 N2066 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2206 C2206 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2766 M2766 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2840 M2840 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T2842 M2842 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K2952 E2952 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3036 N3036 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3042 F3042 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3061 P3061 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S3061 Y3061 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S3207 N3207 Biomuta DOID:363 / uterine cancer [ icgc ]
T3290 N3290 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S3292 F3292 Biomuta DOID:4159 / skin cancer [ cosmic ]
T3466 M3466 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T3466 A3466 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T3528 P3528 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K3652 N3652 Biomuta DOID:363 / uterine cancer [ icgc ]
T3847 I3847 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T3852 A3852 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4015 Y4015 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T4023 M4023 Biomuta DOID:363 / uterine cancer [ cosmic ]
T4097 M4097 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T4097 K4097 Biomuta DOID:4159 / skin cancer [ cosmic ]
T4099 M4099 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S4299 F4299 Biomuta DOID:10534 / stomach cancer [ icgc ]
S4301 C4301 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T4307 A4307 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S4318 P4318 Biomuta [ cosmic ]
S4318 Y4318 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S4318 F4318 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S4349 C4349 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S4349 A4349 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S4349 F4349 Biomuta DOID:4159 / skin cancer [ cosmic ]
T4356 P4356 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S4498 F4498 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S4499 Y4499 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S4499 F4499 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S4500 T4500 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T4516 P4516 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S4527 Y4527 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T4580 I4580 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
N4804 S4804 Biomuta DOID:3571 / liver cancer [ cosmic ]
S5142 Y5142 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S5142 F5142 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]