iPTMnet Report for Q9HC77 (CENPJ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HC77 / CENPJ_HUMAN
Protein Name Centromere protein J
Gene Name Name: CENPJ
Synonyms:CPAP,LAP,LIP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9HC77
DAG View
PRO Name centromere protein J (human)
Definition A centromere protein J that is encoded in the genome of human.
Short Label hCENPJ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HC77 (CENPJ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S53 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S192 Phosphorylation IEDB 35494241
K201 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus   UniProt 23186163
S265 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus   UniProt 23186163
K328 Ubiquitination PhosphoSitePlus
T337 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
K466 Acetylation PhosphoSitePlus
S467 Phosphorylation O14965 (AURKA) PhosphoSitePlus   RLIMS-P+ 26997271
S469 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus   UniProt 23186163
S551 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus
S589 Phosphorylation Q9NYY3 (PLK2) neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20531387
S595 Phosphorylation O00444 (PLK4) , Q9NYY3 (PLK2) neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20531387
C608 Methylation IEDB 31844290
S614 Phosphorylation PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
T616 Phosphorylation PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
T643 Phosphorylation PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
K680 Ubiquitination PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
T682 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
T704 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus   UniProt 21406692
S764 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
K776 Acetylation PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus
S783 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
K790 Acetylation PhosphoSitePlus
T798 Phosphorylation PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
S857 Phosphorylation PhosphoSitePlus
S859 Phosphorylation PhosphoSitePlus
T862 Phosphorylation PhosphoSitePlus
K888 Ubiquitination PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
K929 Ubiquitination PhosphoSitePlus
K979 Ubiquitination PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
S1081 Phosphorylation PhosphoSitePlus
S1109 Phosphorylation PhosphoSitePlus   RLIMS-P 16516142
S1125 Phosphorylation PhosphoSitePlus
K1253 Ubiquitination PhosphoSitePlus
K1296 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S469 Phosphorylation HPRD 19691289
S540 Phosphorylation HPRD 19691289
S556 Phosphorylation HPRD 19691289
S764 Phosphorylation HPRD 19651622
S765 Phosphorylation HPRD 19651622
S785 Phosphorylation HPRD 19007248
S859 Phosphorylation HPRD 19691289
S863 Phosphorylation HPRD 17081983
S892 Phosphorylation HPRD 18077418, 19007248, 19691289
S1109 Phosphorylation HPRD 17924679


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046688 (hCENPJ/Phos:1) pS589,pS595 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S260 Y260 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K308 N308 Biomuta DOID:4362 / cervical cancer [ icgc ]
S316 C316 Biomuta DOID:263 / kidney cancer [ cosmic ]
S497 P497 Biomuta DOID:363 / uterine cancer [ icgc ]
K519 N519 Biomuta DOID:1324 / lung cancer [ icgc ]
S589 L589 Biomuta [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S614 P614 Biomuta DOID:3571 / liver cancer [ cosmic ]
T643 I643 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S683 F683 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S731 T731 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K776 T776 Biomuta DOID:363 / uterine cancer [ icgc ]
S781 L781 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1109 Y1109 Biomuta DOID:363 / uterine cancer [ icgc ]
K1296 E1296 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1296 T1296 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]