iPTMnet Report for Q9HC38 (GLOD4)
Protein Information
UniProt AC / UniProt ID | Q9HC38 / GLOD4_HUMAN |
Protein Name | Glyoxalase domain-containing protein 4 |
Gene Name | Name: GLOD4 Synonyms:C17orf25;ORFNames:CGI-150,My027; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HC38 |
PRO Name | glyoxalase domain-containing protein 4 (human) |
Definition | A glyoxalase domain-containing protein 4 that is encoded in the genome of human. |
Short Label | hGLOD4 |
Category | organism-gene |
Q9HC38 (GLOD4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K12 | Acetylation | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
K181 | Acetylation | score1 | PhosphoSitePlus | |||
C197 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
C221 | S-Nitrosylation | score0 | dbSNO | 19483679, 24105792 | ||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
K234 | Acetylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
T242 | Phosphorylation | score1 | PhosphoSitePlus | |||
S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
T249 | Phosphorylation | score1 | PhosphoSitePlus | |||
C269 | Methylation | score1 | IEDB | 31844290 | ||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
K305 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y23 | Phosphorylation | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
R33 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K12 | E12 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y23 | C23 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K181 | R181 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K224 | N224 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K224 | Q224 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S246 | R246 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S287 | R287 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |