iPTMnet Report for Q9HC21 (SLC25A19)
Protein Information
| UniProt AC / UniProt ID | Q9HC21 / TPC_HUMAN |
| Protein Name | Mitochondrial thiamine pyrophosphate carrier |
| Gene Name | Name: SLC25A19 Synonyms:DNC; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HC21 |
| PRO Name | mitochondrial thiamine pyrophosphate carrier (human) |
| Definition | A mitochondrial thiamine pyrophosphate carrier that is encoded in the genome of human. |
| Short Label | hSLC25A19 |
| Category | organism-gene |
Q9HC21 (SLC25A19) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S51 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S230 | Phosphorylation | score1 | IEDB | 35494241 | ||
| T234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K263 | Acetylation | score1 | PhosphoSitePlus | |||
| K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S286 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T181 | N181 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T181 | P181 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
DAG View