Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HC21 / TPC_HUMAN
Protein Name Mitochondrial thiamine pyrophosphate carrier
Gene Name Name: SLC25A19
Synonyms:DNC,MUP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9HC21
DAG View
PRO Name mitochondrial thiamine pyrophosphate carrier (human)
Definition A mitochondrial thiamine pyrophosphate carrier that is encoded in the genome of human.
Short Label hSLC25A19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HC21 (SLC25A19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus   UniProt 23186163
S53 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
K263 Acetylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S56 C56 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T181 N181 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K263 R263 Biomuta DOID:10534 / stomach cancer [ icgc ]