iPTMnet Report for Q9HC10 (OTOF)
Protein Information
| UniProt AC / UniProt ID | Q9HC10 / OTOF_HUMAN |
| Protein Name | Otoferlin |
| Gene Name | Name: OTOF Synonyms:FER1L2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HC10 |
| PRO Name | otoferlin (human) |
| Definition | An otoferlin that is encoded in the genome of human. |
| Short Label | hOTOF |
| Category | organism-gene |
DAG ViewQ9HC10 (OTOF) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K239 | Acetylation | score1 | PhosphoSitePlus | |||
| T286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y755 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K834 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K896 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1332 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1335 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1340 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1362 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1368 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1532 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1534 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1741 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1753 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1757 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1758 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T1193 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T20 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T149 | M149 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
| S159 | N159 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S177 | F177 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S320 | L320 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] | |
| S320 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S1335 | Y1335 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T1741 | K1741 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S1758 | T1758 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
