iPTMnet Report for Q9HBZ2 (ARNT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HBZ2 / ARNT2_HUMAN
Protein Name Aryl hydrocarbon receptor nuclear translocator 2
Gene Name Name: ARNT2
Synonyms:BHLHE1,KIAA0307;
Organism Homo sapiens (Human)

PRO ID PR:Q9HBZ2
DAG View
PRO Name aryl hydrocarbon receptor nuclear translocator 2 (human)
Definition An aryl hydrocarbon receptor nuclear translocator 2 that is encoded in the genome of human.
Short Label hARNT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HBZ2 (ARNT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R42 Methylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K507 Acetylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
R578 Methylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
S614 Phosphorylation phospho.ELM 18669648
T621 Phosphorylation phospho.ELM 18669648
Site PTM Type PTM Enzyme Score Source PMID
S614 Phosphorylation HPRD 18669648
T621 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R578 L578 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R578 G578 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R578 C578 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
S588 Y588 Biomuta DOID:10534 / stomach cancer [ cosmic ]