Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9HBF4 / ZFYV1_HUMAN
Protein Name Zinc finger FYVE domain-containing protein 1
Gene Name Name: ZFYVE1
Organism Homo sapiens (Human)

DAG View
PRO Name zinc finger FYVE domain-containing protein 1 (human)
Definition A zinc finger FYVE domain-containing protein 1 that is encoded in the genome of human.
Short Label hZFYVE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9HBF4 (ZFYVE1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S129 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
R753 Methylation PhosphoSitePlus
R765 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T369 M369 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S599 Y599 Biomuta DOID:3571 / liver cancer [ icgc ]
R753 L753 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R765 * Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]