iPTMnet Report for Q9HBF4 (ZFYVE1)
Protein Information
| UniProt AC / UniProt ID | Q9HBF4 / ZFYV1_HUMAN |
| Protein Name | Zinc finger FYVE domain-containing protein 1 |
| Gene Name | Name: ZFYVE1 Synonyms:DFCP1,KIAA1589,TAFF1,ZNFN2A1;ORFNames:PP10436; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HBF4 |
| PRO Name | zinc finger FYVE domain-containing protein 1 (human) |
| Definition | A zinc finger FYVE domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hZFYVE1 |
| Category | organism-gene |
Q9HBF4 (ZFYVE1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T107 | O-Glycosylation | score1 | GlyGen | 35254053 | ||
| S109 | O-Glycosylation | score1 | GlyGen | 35254053 | ||
| S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T369 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T386 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K487 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S599 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S632 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S633 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T665 | O-Glycosylation | score1 | GlyGen | 32938750 | ||
| R753 | Methylation | score1 | PhosphoSitePlus | |||
| R765 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T369 | M369 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| R753 | L753 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| R765 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View