iPTMnet Report for Q9HB96 (FANCE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HB96 / FANCE_HUMAN
Protein Name Fanconi anemia group E protein
Gene Name Name: FANCE
Synonyms:FACE;
Organism Homo sapiens (Human)

PRO ID PR:Q9HB96
DAG View
PRO Name Fanconi anemia group E protein (human)
Definition A Fanconi anemia group E protein that is encoded in the genome of human.
Short Label hFANCE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HB96 (FANCE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K84 Ubiquitination PhosphoSitePlus
R142 Methylation PhosphoSitePlus
S154 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
R159 Methylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S247 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S249 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...19664994, 18452278, 18669648, 19690332
K252 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K272 Methylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
T346 Phosphorylation O14757 (CHEK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17296736
S374 Phosphorylation O14757 (CHEK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17296736
C391 Methylation IEDB 31844290
Y489 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S180 F180 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S204 L204 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K252 R252 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K272 N272 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y489 F489 Biomuta DOID:1612 / breast cancer [ cosmic ]