iPTMnet Report for Q9HB09 (BCL2L12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HB09 / B2L12_HUMAN
Protein Name Bcl-2-like protein 12
Gene Name Name: BCL2L12
Synonyms:BPR;
Organism Homo sapiens (Human)

PRO ID PR:Q9HB09
DAG View
PRO Name Bcl-2-like protein 12 (human)
Definition A Bcl-2-like protein 12 that is encoded in the genome of human.
Short Label hBCL2L12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HB09 (BCL2L12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S113 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
T117 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S121 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
R144 Methylation PhosphoSitePlus   UniProt 24129315
C155 Methylation IEDB 31844290
S156 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 22262180, 29749471
S156 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 22262180
T171 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus   UniProt 23186163
K206 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S242 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18578522, 17081983, 21406692, ...19651622, 18669648, 20166139, 20068231
S243 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 18578522
S245 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18578522, 23186163
S273 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 18578522, 23186163, ...19664994, 19664995
Site PTM Type PTM Enzyme Score Source PMID
S113 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S120 R120 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S121 R121 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R144 * Biomuta [ cosmic ]
S156 C156 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S243 P243 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S245 Y245 Biomuta DOID:9256 / colorectal cancer [ cosmic ]