iPTMnet Report for Q9HAZ2 (PRDM16)
Protein Information
| UniProt AC / UniProt ID | Q9HAZ2 / PRD16_HUMAN |
| Protein Name | Histone-lysine N-methyltransferase PRDM16 |
| Gene Name | Name: PRDM16 Synonyms:KIAA1675; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HAZ2 |
| PRO Name | histone-lysine N-methyltransferase PRDM16 (human) |
| Definition | A histone-lysine N-methyltransferase PRDM16 that is encoded in the genome of human. |
| Short Label | hPRDM16 |
| Category | organism-gene |
Q9HAZ2 (PRDM16) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y194 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K321 | Sumoylation | score1 | PhosphoSitePlus | |||
| K335 | Acetylation | score1 | PhosphoSitePlus | |||
| S379 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K382 | Sumoylation | score1 | PhosphoSitePlus | |||
| T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T464 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S537 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S581 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S586 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T611 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K778 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T876 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K915 | Acetylation | score1 | PhosphoSitePlus | |||
| T974 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S989 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1089 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1090 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1194 | Acetylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K568 | Sumoylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S44 | L44 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] | |
| Y194 | C194 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| T421 | M421 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T435 | I435 | Biomuta | DOID:10283 / prostate cancer [ icgc ] | |
| T435 | A435 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S537 | I537 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S586 | P586 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| T611 | M611 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View