iPTMnet Report for Q9HAW0 (BRF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HAW0 / BRF2_HUMAN
Protein Name Transcription factor IIIB 50 kDa subunit
Gene Name Name: BRF2
Synonyms:BRFU;ORFNames:PRO1470;
Organism Homo sapiens (Human)

PRO ID PR:Q9HAW0
DAG View
PRO Name transcription factor IIIB 50 kDa subunit (human)
Definition A transcription factor IIIB 50 kDa subunit that is encoded in the genome of human.
Short Label hBRF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HAW0 (BRF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C80 Methylation IEDB 31844290
T140 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
C168 Methylation IEDB 31844290
C177 Methylation IEDB 31844290
S188 O-Glycosylation GlyGen 30379171
K192 Ubiquitination PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
S353 Phosphorylation IEDB   PhosphoSitePlus   UniProt 27920218, 23186163
S365 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S385 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T140 P140 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S150 C150 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
C177 F177 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T218 N218 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y260 C260 Biomuta [ cosmic ]